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Applied Biomics

Serving Your Proteomics Needs

Applied Biomics is a Proteomics service company established in 2005. We are dedicated to providing top-quality, cost-effective and full-line Proteomics services, from sample preparation to generating high quality data for publications (all listed services are performed in house):

GEL-BASED PROTEOMICS: 2D DIGE & 2D WESTERN
Customized Experimental Design
Sample Preparation
2D DIGE Global Protein Expression Profiling
2D DIGE Phospho-Protein Expression Profiling
Serum Proteomics
Host Cell Protein (HCP) Assay
2D Fluorescent Western Blot
PTM 2D Western Blot
Data Analysis

LIQUID-BASED PROTEOMICS SERVICES
iTRAQ® (2-8 plex)
NanoLC-MS/MS

MASS SPECTROMETRY SERVICES
Protein Identification by MALDI TOF/TOF
Identification of Phosphorylation Site
Identification of Acetylation Site
   De Novo Peptide Sequencing

IN ADDITION, WE ALSO OFFER
1D Gel Quantitative Western Blot
 Immuno-Depletion of Serum Abundant Proteins
Different Staining of 2D Gels
Customized and Contract Research
  And more ...

HCP
HCP Western Blot

2D Dige Image
2D DIGE

Protein phosphorylation staining
2D Phospho-staining

In-gel data analysis
2D In-gel Analysis

Cross-gel data analysis
Cross-gel Analysis

Protein identification by mass spect
Protein ID by Mass Spec

Serum proteomics
Serum 2D DIGE
iTRAQ
iTRAQ
2D western blot
2D DIGE & Western Blot

WHY US ?

High quality: >385 publications
Quick turnaround
Cost effective
Complimentary experimental design
Proprietary sample preparations
All in-house services
Excellent support

NEW CUSTOMERS

Getting Started

Up to 15% discount on the first 2D DIGE analytical gel

2D DIGE vs. 2D GEL

Why run 2D DIGE instead of 2D gels? What are the advantages of 2D DIGE over traditional 2D gels? Click to see the answer.

Selected Proteomics Publications Using Applied Biomics 2D DIGE/ Mass Spectrometry Services
(Over 200 Publications in Recent 5 Years)

388. Hongjiao Li, Yi Wang, Xingchen Pang, Chenglian Xie, H. Joachim Deeg, Hui Wang, Ting Wan, Jinpeng Wu, Feng Guan, and Xiang Li (2020) Elevated TWIST1 expression in myelodysplastic syndromes/ acute myeloid leukemia reduces efficacy of hypomethylating therapy with decitabine. Haematologica 105: doi:10.3324

387. Hyunsoo Kim, Matthew C. Walsh, Jiyeon Yu, Paul Laskoski Kei Takigawa, Noriko Takegahara, Yongwon Choi (2020) Methylosome protein 50 associates with the purinergic receptor P2X5 and is involved in osteoclast maturation. FEBS Lett. 594 (1): 144-152. DOI: 10.1002/1873-3468.13581.

386. Tino W Sanchez, Bo Li, Christine Molinaro, Carlos A Casiano, Denise L Bellinger, Eugenia Mata-Greenwood (2020) Maternal Plasma Proteomics in a Rat Model of Pregnancy Complications Reveals Immune and Pro-Coagulant Gene Pathway Activation. Am J Reprod Immunol. 83 (2), e13205. PMID: 31677200 DOI: 10.1111/aji.13205.

385. S.D. Todorov V.Q. Cavicchioli M. Ananieva V.P. Bivolarski T.A. Vasileva A.V. Hinkov D.G. Todorov S. Shishkov T. Haertlé I.N. Iliev L.A. Nero I.V. Ivanova (2020) Expression of coagulin A with low cytotoxic activity by Pediococcus pentosaceus ST65ACC isolated from raw milk cheese. J Appl Microbiol 128: 458-472. https://doi.org/10.1111/jam.14492.

384. Xuping Li et al. (2020) OCIAD1 contributes to neurodegeneration in Alzheimer’s disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages. EBioMedicine 2020 Jan 10;51:102569, DOI:https://doi.org/10.1016/j.ebiom.2019.11.030.

More Applied Biomics Publications