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2D DIGE Cross-gel Analysis: Drug Toxicity Biomarkers

 

 

 

Green: Control
Red: Drug 1

2D DIGE Cross-gel Analysis: Drug Toxicity Biomarkers

Green: Control
Red: Drug 2

2D DIGE Cross-gel Analysis: Drug Toxicity Biomarkers

Green: Drug 1
Red: Drug 2

2D DIGE Cross-gel Analysis: Drug Toxicity Biomarkers

Green: Control
Red: Drug 3

2D DIGE Cross-gel Analysis: Drug Toxicity Biomarkers
Green: Control
Red: Drug 4

2D DIGE Cross-gel Analysis: Drug Toxicity Biomarkers
Green: Drug 3
Red: Drug 4

2D DIGE Cross-gel Analysis: Drug Toxicity Biomarkers

 

Clustering Analysis of Protein Toxic-marker Expression
Patterns for Toxic Compounds (1480 spots)

Clustering Analysis of Protein Toxic-marker Expression

 

The change in expression level between control and drug treatment for 1480 protein spots is shown for each of the 18 drugs, which are grouped according to toxicity. Cluster analysis was performed with Genespring software ( Redwood City, CA).